BCN LUMEN PEPTIDES – Advanced Whitening Cocktail melanogenic factors, inhibits melanin synthesis and increases cell detoxification. These actions have the following effects:
Peptides: Decapeptide-15, Oligopeptide-34, Oligopeptide-51, Oligopeptide-58, Oligopeptide-68
TREATMENTS: Hyperpigmentation, Whitening treatment softens pigmentation on face and body acting on all stages of the melanin pathway.
PRESENTATION: Vial | 5 ml | 0,176 fl. oz. | Box of 5 vials | Mesotherapy serum
For professional and experienced training in mesotherapy only.
Administration: Transdermal with virtual mesotherapy (electroporation, iontoforesis) or with superficial subcutaneous micro injections or with Derma Roller. Administering superficial subcutaneous micro injections or by traditional mesotherapy method depends on the legislation of each country and has to be performed by medically trained staff.
The formula of BCN LUMEN PEPTIDES clears existing pigmentations and prevents the production of new ones on face and body acting on all stages of the melanin creation process beginning with the signalling pathway. Different classic hipopigmenting actives together with new age peptides synergize with to down-regulate melanogenic factors, inhibit melanin synthesis, increase cell detoxification and reduce melanosome to keratinocyte transfer. It impacts on facultative and constitutive pigmentations.
Hyaluronic Acid, Vitamins, Minerals, Amino acids, etc. take care of the overall skin health with their revitalizing, hydrating and collagen expression boosting actions.
Useful to fight against: tans, melasma, age spots, pregnancy pigmentations, post-inflammatory hyperpigmentations.
Advanced Whitening Cocktail
Skin pigmentation is caused by the synthesis of melanin by the melanocytes through a process called melanogenesis. After the melanin pigments are synthesized, they are then transferred to the keratinocytes (the most abundant cells on the skin surface), in cellular vesicles called melanosomes. The more melanosomes that reach the keratinocytes on the surface, the darker the skin becomes. In fact, the skin produces two types of melanin: pheomelanin, in people with pale skin and red hair and eumelanin, in people with darker skin and hair and people with black skin.
Melanin synthesis is produced from the amino acid tyrosine. Tyrosine, in the presence of the enzyme tyrosinase and oxygen, is oxidized to dopa, which, in turn, is oxidized to dopaquinone. The dopaquinone then spontaneously converts to leucodopachrome, which easily oxidates to dopachrome. The dopachrome loses its carboxyl and is reorganised to form melanin.
The combination of active ingredients in BCN LUMEN PEPTIDES acts on all stages of this process of melanin production in order to achieve a depigmenting, lightening and balancing effect on the skin, thanks to the synergistic and combined action of the three types of active ingredients: the new generation biopeptides (oligopeptides 51, 34 and 58, the decapeptide 15 and the acetyl-glycine-beta-alanine), the pigment-removing tyrosinase inhibitors (α-arbutin and extract of liquorice root) and the anti-oxidants, such as ascorbic acid, thioctic acid, vitamin B3 and glutathione.
BCN LUMEN PEPTIDES reduces melanogenic factors, inhibits melanin synthesis and increases cell detoxification. These actions have the following effects:
A reduction in melasma (excess pigmentation).
A reduction in age spots.
A reduction in hyperpigmentation during pregnancy.
A reduction in post-inflammatory hyperpigmentation.
The function and mechanism of action of each component is as follows:
Oligopeptide-51, whose lightening effect is due to its inhibitory action at a cellular level of the microphthalmia-associated transcription factor (MITF), which is the master gene for melanocytic survival and a key factor in regulating transcription of the proteins which generate melanin in the physiology of normal pigmented cells, such as proteins related to type 1 and type 2 tyrosinases (TRP 1 y TRP 2). The result is a reduction in both the transcription factor and the tyrosinases. It also inhibits expression of the markers of melanogenesis and induces morphological changes in the melanocytes.
Oligopeptide-34, also acts by inhibiting melanin synthesis by reducing both the MITF factor and the tyrosinase-related proteins 1 and 2. This peptide also acts on the melanosomes, reducing their levels and blocking the transfer of pigment from the melanosomes to the keratinocytes. In addition, the oligopeptide-34 has an anti-inflammatory effect, as on the one hand it reduces the proliferation of activated T cells and lowers the volume of proinflammatory cytokines, as well as their level of transcription, translation and expression where the inflammation is due to the polysaccharide endotoxines. On the other hand, it reduces translocation to the p65 subunit nucleus of the protein complex, nuclear factor kappa-light-chain-enha